1.Nazari, S., Mosaffa, F., Poustforoosh, A., Mortazavi, M., Saso, L., Firuzi, O., Moosavi, F. "Foretinib, a c-MET receptor tyrosine kinase inhibitor, tackles multidrug resistance in cancer cells by inhibiting ABCB1 and ABCG2 transporters.Toxicol. Appl. Pharmacol.2024 15:116866 (2024).
2.Firouzi, M., Haghighijoo, Z., Eskandari, M., Mohabbati, M., Miri, R., Jamei, M.H., Poustforoosh, A., Nazari, S., Firuzi, O., Khoshneviszadeh, M., Edraki, N. "Synthesis and cytotoxic activity evaluation of novel imidazopyridine carbohydrazide derivatives.BMC Chem.18(1):6 (2024).
3.Abbaspour, A., Dehghani, M., Setayesh, M., Tavakkoli, M., Rostamipour, H.A., Ghorbani, M., Ramzi, M., Omidvari, S., Moosavi, F., Firuzi, O.* (*Corresponding author) "Cytidine deaminase enzyme activity is a predictive biomarker in gemcitabine-treated cancer patients".Cancer Chemother. Pharmacol.doi: 10.1007/s00280-023-04579-8 (2023).
4.Mortazavi, M., Eskandari, M., Moosavi, F., Damghani, T., Khoshneviszadeh, M., Pirhadi, S., Saso, L., Edraki, N., Firuzi, O.* (*Corresponding author) "Novel quinazoline-1,2,3-triazole hybrids with anticancer and MET kinase targeting properties."Sci. Rep.13(1):14685. doi: 10.1038/s41598-023-41283-2 (2023).
5. Ranjbar, S., Lashkarian, F.F., Khoshneviszadeh, M., Moosavi, F., Damghani, T., Firuzi, O.*, Edraki, N. (*Corresponding author) Oxohexahydroquinolines bearing 4-pyridyl methyl carboxylate as P-glycoprotein inhibitors and multidrug resistance reversal agents in cancer cells.J. Mol. Struct.1285:135427 (2023).
6. Divar, M., Edraki, N., Damghani, T., Moosavi, F., Mohabbati, M., Alipour, A., Pirhadi, S., Saso, L., Khabnadideh, S., Firuzi, O.* (*Corresponding author) "Novel spiroindoline quinazolinedione derivatives as anticancer agents and potential FLT3 kinase inhibitors.Bioorg. Med. Chem.15(90):117367 (2023).
7.Kazemi, M., Parhizkar, E., Samani, S.M., Firuzi, O., Sadeghpour, H., Ahmadi, F., Dehshahri, A."Targeted co-delivery of paclitaxel and anti P-gp shRNA by low molecular weight PEI decorated with L-3,4-dihydroxyphenylalanine" Biotechnol. Prog.39(2):e3310 (2023).
8.Hafez Ghoran, S., Firuzi, O., Pirhadi, S., Khattab, O.M., El-Seedi, H.R., Jassbi, A.R."Sappanin-type homoisoflavonoids from Scilla bisotunensis Speta.: Cytotoxicity, molecular docking, and chemotaxonomic significance." J. Mol. Struct.127:134326 (2023).
9. Mortazavi, M., Raufi, E., Damghani, T., Khoshneviszadeh, M., Edraki, N., Eskandari, M., Giovannetti, E., Peters, G.J., Pirhadi, S., Firuzi, O.* (*Corresponding author)Discovery of anticancer agents with c-Met inhibitory potential by virtual and experimental screening of a chemical library. Eur. J. Pharmacol.938:75395 (2023).
10.Iraji, I., Shahrokh, N., Firuzi, O., Mohabbati, M., Miri, M., Sadeghpour, H., Khoshneviszadeh, M., Edraki, N."Acenaphthotriazine Thio-triazole Derivatives as Anti-cancer Agents Triggering Cell Cycle Arrest in Breast Cancer Cells."Lett. Drug Des. Discov.20(6):639-648 (2023).
11.Saeedi, M., Iraji, A., Vahedi-Mazdabadi, Y., Alizadeh, A., Edraki, N., Firuzi, O., Eftekhari, M., Akbarzadeh, T. "Cinnamomum verum J. Presl. Bark essential oil: in vitro investigation of anti-cholinesterase, anti-BACE1, and neuroprotective activity."BMC Complement. Med. Ther.22(1):303 (2022).
12.Nazemosadat-Arsanjani, Z., Moein, M., Yousuf, S., Firuzi, O., Choudhary, M.I."Reassessing the molecular structures of some previously isolated abietane diterpenoids with a naphthalene moiety and the structure-activity relationship (SAR) of quinone diterpenoids."Phytochemistry. 204:113433 (2022).
13.Noorbakhsh, F., Zare, S., Firuzi, O., Sakhteman, A., Chandran, J.N., Schneider, B., Jassbi, A.R."Phytochemical Analysis and Biological Activity of Salvia compressa Vent Iran. J Pharm. Res. 21(1):e127031 (2022).
14.Mortazavi M, Divar M, Damghani T, Moosavi F, Saso L, Pirhadi S, Khoshneviszadeh M, Edraki N, Firuzi, O.* (*Corresponding author) Study of the anticancer effect of new quinazolinone hydrazine derivatives as receptor tyrosine kinase inhibitors.Front. Chem.2022 10:969559 (2022).
15.Mehdizadeh Naderi, P., Zargoosh, K., Qandalee, M., Firuzi, O., Behmadi, H., Hossienkhani, S., Moasses Ghafary, S., Durán-Valle, C.J. Synthesis and application of the fluorescent furan and imidazole probes for selective in vivo and in vitro cancer cell imaging.Spectrochim. Acta A. Mol. Biomol. Spectrosc.279:121455 (2022).
16.Mortazavi, M., Moosavi, F., Martini, M., Giovannetti, E., Firuzi, O.* (*Corresponding author) Prospects of targeting PI3K/AKT/mTOR pathway in pancreatic cancer.Crit. Rev. Oncol. Hematol.176:103749 (2022).
17.Ranjbar, S., Khoshneviszadeh, M., Tavakkoli, M., Miri, R., Edraki, N., Firuzi, O.* (*Corresponding author) 5-Oxo-hexahydroquinoline and 5-oxo-tetrahydrocyclopentapyridine derivatives as promising antiproliferative agents with potential apoptosis-inducing capacity.Mol. Divers.26(3):1481-1500 (2022).
18.Synthesis and evaluation of novel arylisoxazoles linked to tacrine moiety: in vitro and in vivo biological activities against Alzheimer’s disease.
Rastegari, A., Safavi, M., Vafadarnejad, F., Najafi, Z., Hariri, R., Bukhari, S.N.A., Iraji, A., Edraki, N., Firuzi, O., Saeedi, M., Mahdavi, M., Akbarzadeh, T.Mol. Divers.26(1):409-428 (2022).
19.Attarroshan, M., Firuzi, O., Iraji, A., Sharifi, S., Tavakkoli, M., Vesal M., Khoshneviszadeh M., Pirhadi, S., Edraki, N. Imino-2H-Chromene Based Derivatives as Potential Anti-Alzheimer's Agents: Design, Synthesis, Biological Evaluation andin SilicoStudy.Chem. Biodivers.16:e2100599 (2022).
20.Jassbi, A.R., Hadavand Mirzaei, H., Firuzi, O., Pirhadi, S., Asadollahi, M., Chandran, J.N., Schneider, B. Cytotoxic abietane-type diterpenoids from roots ofSalvia spinosaand theirin Silicopharmacophore modeling.Nat. Product. Res.22:1-6 (2022).
21.Heidary Jamebozorgi, F., Yousefzadi, M., Firuzi, O., Nazemi, M., Zare, S., Chandran, J.N., Schneider, B., Baldwin, I.T., Jassbi, A.R. Cytotoxic furanosesquiterpenoids and steroids from Ircinia mutans sponges.Pharm. Biol.59(1):575-583 (2021).
22.Edraki N., Jamei M.H., Haghighijoo Z., Kayani Z., Raufi E., Eskandari M., Firouzi M., Sadeghpour H., Miri R., Khoshneviszadeh M., Firuzi, O.* (*Corresponding author) Phenanthrotriazine Derivatives Containing Arylidine Hydrazone Moieties as Novel Potential c-Met Inhibitors with Anticancer Effect.Iran. J. Pharm. Res.20: 516-531 (2021).
23.Khoshneviszadeh, M., Firuzi, O., Aminsafaee, M., Kashefizadeh, M., Ranjbar, S., Rezaei, Z., Sadeghpour, H., Zargari, F., Miri, R., Edraki, N. Novel Cytotoxic Phenanthro-triazine-3-thiol Derivatives as Potential DNA Intercalators and Bcl-2 Inhibitors.Iran. J. Pharm. Res.20(3):161-177 (2021).
24.Moheimanian, N., Firuzi, O., Sohrabipour, J., Jassbi, A.R. Assessment of Phenolic Contents and Antibacterial, Cytotoxic, and Antioxidant Activities of Five Brown Algae from the Persian Gulf.Iran. J. Sci. Technol. Transact. A: Sci.45:1869-1877 (2021).
25.Damghani, T., Moosavi, F., Khoshneviszadeh, M., Mortazavi, M., Pirhadi, S., Kayani, Z., Saso, L., Edraki, N., Firuzi, O.* (*Corresponding author) Imidazopyridine hydrazine derivatives exert antiproliferative effect on lung and pancreatic cancer cells and potentially inhibit receptor tyrosine kinases including c‑Met.Sci. Rep.11:3644 (2021).
26.Saeedi, M., Maleki, A., Iraji, A., Hariri, R., Akbarzadeh, T., Edraki, N., Firuzi, O., Mirfazli, S. Synthesis and bio-evaluation of new multifunctional methylindolinone-1,2,3-triazole hybrids as anti-Alzheimer's agents.J. Mol. Struct.1229:129828 (2021).
27.Moosavi, F., Giovannetti, E., Peters, G.J., Firuzi, O.* (*Corresponding author) Combination of HGF/MET-targeting agents and other therapeutic strategies in cancer.Crit. Rev. Oncol. Hematol.160:103234 (2021).
28.Hafez Ghoran, S., Firuzi, O., Asadollahi, M., Stuppner, H., Alilou, M., Jassbi, A.R.Dammarane-type triterpenoid saponins from Salvia russellii Benth.Phytochemistry184:112653 (2021).
29.Zare, S., Hatam, G., Firuzi, O., Bagheri, A., Chandran, J.N., Schneider, B., Paetz, C., Pirhadi, S., Jassbi, A.R. Antileishmanial and pharmacophore modeling of abietane-type diterpenoids extracted from the roots of Salvia hydrangea.J. Mol. Struct.1228:129447 (2021).
30.Moosavi, F., Ebadi, A., Mohabbati, M., Damghani, T., Mortazavi, M., Miri, R., Firuzi, O.* (*Corresponding author) Antiproliferative effect, alteration of cancer cell cycle progression and potential MET kinase inhibition induced by 3,4-dihydropyrimidin-2(1H)-one C5 amide derivatives.Eur. J. Pharmacol.894:173850 (2021).
31.Saeedi, M., Felegari, P., Iraji, A., Hariri, R., Rastegari, A., Mirfazli, S.S., Edraki, N., Firuzi, O., Mahdavi, M., Akbarzadeh, T. Novel N-benzylpiperidine derivatives of 5-arylisoxazole-3-carboxamides as anti-Alzheimer's agents. Arch. Pharm.354(3):2000258 (2021).
32.Viayna, E., Coquelle, N., Cieslikiewicz-Bouet, M., Cisternas, P., Oliva, C.A., Sánchez-López, E.f, Ettcheto, M., Bartolini, M., De Simone, A., Ricchini, M., Rendina, M., Pons, M., Firuzi, O., Pérez, B., Saso, L., Andrisano, V., Nachon, F., Brazzolotto, X., García, M.L., Camins, A., Silman, I., Jean, L., Inestrosa, N.C., Colletier, J.-P., Renard, P.-Y., Muñoz-Torrero, D. Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice.J. Med. Chem.64(1):812-839 (2021).
33.Ranjbar, S., Khoshneviszadeh, M., Tavakkoli, M., Miri, R., Edraki, N., Firuzi, O.* (*Corresponding author) 5-Oxo-hexahydroquinoline and 5-oxo-tetrahydrocyclopentapyridine derivatives as promising antiproliferative agents with potential apoptosis-inducing capacity Mol. Divers. (2021).
34.Ranjbar, S., Shabanpoor, M.R., Dehghani, Z., Firuzi, O., Edraki, N., Khoshneviszadeh, M.Braz. J. Pharm. Sci.57:18074 (2021). Dihydronaphthalenone chalconoid derivatives as potential cathepsin b inhibitors; design, synthesis, cytotoxicity evaluation and docking analysis.
35.Abbasi, S., Yousefi, G., Tamaddon, A.M., Firuzi, O. Paclitaxel-loaded polypeptide-polyacrylamide nanomicelles overcome drug-resistance by enhancing lysosomal membrane permeability and inducing apoptosis.J. Biomed. Mater. Res. A. 109(1):18-30 (2021).
36.Haghighijoo, Z., Firuzi, O., Meili, S., Edraki, N., Khoshneviszadeh, M., Miri, R. Design and synthesis of novel 1-hydroxy-2,4,5-triaryl imidazole derivatives as anti-cytokine agents. Iran. J. Pharm. Res.19(1):181-191 (2020).
37.Karimi Askarani, H., Iraji, A., Rastegari, A., Abbas Bukhari, S., Firuzi, O., Akbarzadeh, T., Saeedi, M. Design and synthesis of multi-target directed 1,2,3-triazole-dimethylaminoacryloyl-chromenone derivatives with potential use in Alzheimer's disease.BMC Chem.14(1):64 (2020).
38.Zare, S., Mirkhani, H., Firuzi, O., Moheimanian, N., Asadollahi, M., Pirhadi, S., Chandran, J.N., Schneider, B., Jassbi, A.R. Antidiabetic and cytotoxic polyhydroxylated oleanane and ursane type triterpenoids from Salvia grossheimii. Bioorg. Chem.104:104297 (2020).
39.Saeedi, M., Safavi, M., Allahabadi, E., Rastegari, A., Hariri, R., Jafari, S., Bukhari, S.N.A., Mirfazli, S.S., Firuzi, O., Edraki, N., Mahdavi, M., Akbarzadeh, T. Thieno[2,3-b]pyridine amines: Synthesis and evaluation of tacrine analogs against biological activities related to Alzheimer's disease. Arch. Pharm.353(10):2000101 (2020).
40.Che, P.P., Gregori, A., Firuzi, O., Dahele, M., Sminia, P., Peters, G.J. Giovannetti, E. Pancreatic cancer resistance conferred by stellate cells: looking for new preclinical models.Exp. Hematol. Oncol.9:18 (2020).
41.Yazdani, M., Edraki, N., Badri, R., Khoshneviszadeh, M., Iraji, A., Firuzi, O. 5,6-Diphenyl triazine-thio methyl triazole hybrid as a new Alzheimer's disease modifying agents. Mol. Divers.24(3):641-654 (2020).
42.Saeedi, M., Rastegari, A., Hariri, R., Mirfazli, S.S., Mahdavi, M., Edraki, N., Firuzi, O., Akbarzadeh, T. Design and synthesis of novel arylisoxazole-chromenone carboxamides: Investigation of biological activities associated with Alzheimer's disease.Chem. Biodivers.17(5):e1900746 (2020).
43.Iraji, A., Khoshneviszadeh, M., Firuzi, O., Khoshneviszadeh, M., Edraki N. Novel small molecule therapeutic agents for Alzheimer disease: Focusing on BACE1 and multi-target directed ligands. Bioorg. Chem.97:103649 (2020).
44.Cunha-Oliveira, T., Montezinho, L., Mendes, C., Firuzi, O., Saso, L., Oliveira, P.J., Silva, F.S.G. Oxidative Stress in Amyotrophic Lateral Sclerosis: Pathophysiology and Opportunities for Pharmacological Intervention. Oxid. Med. Cell. Longev.2020:5021694 (2020).
45.Shahraki, O., Khoshneviszadeh, M., Dehghani, M., Mohabbati, M., Tavakkoli, M., Saso, L., Edraki, N., Firuzi, O.* (*Corresponding author) 5-Oxo-hexahydroquinoline derivatives and their tetrahydroquinoline counterparts as multidrug resistance reversal agents. Molecules25(8). pii: E1839. (2020).
46.Hadavand Mirzaei, H., Jassbi, A.R., Pirhadi, S., Firuzi, O.* (*Corresponding author)Study of the mechanism of action, molecular docking, and dynamics of anticancer terpenoids from Salvia lachnocalyx. J. Recept. Signal. Transduct. Res. 40(1):24-33 (2020).
47.Ghoran, S.H., Firuzi, O., Jassbi, A.R. Phytoconstituents from the aerial parts of Salvia dracocephaloides boiss. and their biological activities. J. Environ. Treat. Tech.8(4):1274-1278 (2020)
48.Azimi, S., Firuzi, O., Iraji, A., Zonouzi, A., Khoshneviszadeh, M., Mahdavi, M., Edraki, N. Synthesis and in vitro biological activity evaluation of novel imidazo [2,1-B][1,3,4] thiadiazole as anti-Alzheimer agents.Lett. Drug Des. Discov.17(5):608-615 (2020).
49.Akrami, H., Mirjalili, B., Firuzi, O., Hekmat, A., Sab-Oury, A.A., Miri, R., Sabzevari, O., Pirali-Hamedani, M., Jeivad, F., Moghimi, S., Emami, S., Foroumadi, A., Khoobi, M. Cytotoxic activity and DNA binding property of new aminopyrimidine derivatives. Lett. Drug Des. Discov.17(5):638-652 (2020).
50.Fathalipour, M., Eghtedari, M., Borges, F., Silva, T., Moosavi, F., Firuzi, O., Mirkhani, H. Caffeic acid alkyl amide derivatives ameliorate oxidative stress and modulate ERK1/2 and Akt signaling pathways in a rat model of diabetic retinopathy.Chem. Biodivers.16(12):e1900405 (2019).
51.Moosavi, F., Giovannetti, E., Saso, L., Firuzi, O.* (*Corresponding author) HGF/MET pathway aberrations as diagnostic, prognostic, and predictive biomarkers in human cancers.Crit. Rev. Clin. Lab. Sci.12:1-34 (2019).
52.Vafadarnejad, F., Karimpour-Razkenari, E., Sameem, B., Saeedi, M., Firuzi, O., Edraki, N., Mahdavi, M., Akbarzadeh, T. Novel N-benzylpyridinium moiety linked to arylisoxazole derivatives as selective butyrylcholinesterase inhibitors: Synthesis, biological evaluation, and docking study.Bioorg. Chem.92:103192 (2019).
53.Asadollahi, M., Firuzi, O., Heidary Jamebozorgi, F., Alizadeh, M., Jassbi, A.R. Ethnopharmacological studies, chemical composition, antibacterial and cytotoxic activities of essential oils of eleven Salvia in Iran. J. Herb. Med.17-18:100250 (2019).
54.Damghani, T., Mashayekh, K., Pirhadi, S., Firuzi, O., Sharifi, S., Edraki, N., Khoshneviszadeh, M., Avestan, M.S. Prediction of cytotoxic activity of a series of 1H-pyrrolo[2,3-b]pyridine derivatives as possible inhibitors of c-Met using molecular fingerprints. J. Recept. Signal Transduct. Res.28:1-9 (2019).
55.Gholampour, M., Ranjbar S., Edraki, N., Mohabbati M., Firuzi O., Khoshneviszadeh, M. Click chemistry-assisted synthesis of novel aminonaphthoquinone-1,2,3-triazole hybrids and investigation of their cytotoxicity and cancer cell cycle alterations. Bioorg. Chem.88:102967 (2019).
56.Heidary Jamebozorgi, F., Yousefzadi, M., Firuzi, O., Nazemi, M., Jassbi, A.R. In vitro anti-proliferative activities of the sterols and fatty acids isolated from the Persian Gulf sponge; Axinella sinoxea. DARU J. Pharmac. Sci.27:121-135 (2019).
57.Ranjbar, S., Edraki, N., Firuzi, O., Khoshneviszadeh, M., Miri, R. 5-Oxo-hexahydroquinoline: an attractive scaffold with diverse biological activities. Mol. Divers.23:471-508 (2019).
58.Firuzi, O., Che, P.P., El Hassouni, B., Buijs, M., Coppola, S., Löhr, M., Funel, N., Heuchel, R., Carnevale, I., Schmidt, T., Mantini, G., Avan, A., Saso, L., Peters, G.J., Giovannetti, E. Role of c-MET Inhibitors in Overcoming Drug Resistance in Spheroid Models of Primary Human Pancreatic Cancer and Stellate Cells. Cancers11(5):638 (2019).
59.Mahdavi, M., Hariri, R., Mirfazli, S.S., Lotfian, H., Rastergari, A., Firuzi, O., Edraki, N., Larijani, B., Akbarzadeh, T., Saeedi, M. Synthesis and biological activity of some benzochromenoquinolinones: Tacrine analogues as potent anti-Alzheimer's agents.Chem. Biodivers.16(4):e1800488 (2019).
60.Yazdani, M., Edraki, N., Badri, R., Khoshneviszadeh, M., Iraji, A., Firuzi, O. Multi-target inhibitors against Alzheimer disease derived from 3-hydrazinyl 1,2,4-triazine scaffold containing pendant phenoxy methyl-1,2,3-triazole: Design, synthesis and biological evaluation. Bioorg. Chem.84:363-371 (2019).
61.Mostoufi, H., Yousefi, G., Tamaddon, A.M., Firuzi, O. Reversing multi-drug tumor resistance to Paclitaxel by well-defined pH-sensitive amphiphilic polypeptide block copolymers via induction of lysosomal membrane permeabilization.Colloids Surf. B Biointerfaces.174:17-27 (2019).
62.Hadavand Mirzaei, H., Firuzi, O., Chandran, J.N., Schneider, B., Jassbi, A.R. Two antiproliferative seco-4,5-abietane diterpenoids from roots of Salvia ceratophylla L. Phytochem. Lett.29:129-133 (2019).
63.Saeedi, M., Mohtadi-Haghighi, D., Mirfazli, S.S., Mahdavi, M., Hariri, R., Lotfian, H., Edraki, N., Iraji, A., Firuzi, O., Akbarzadeh, T. Design and synthesis of selective acetylcholinesterase inhibitors: arylisoxazole-phenylpiperazine derivatives. Chem. Biodivers.16:e1800433 (2019).
64.Karaaslan, C., Ince, E., Gurer-Orhan, H., Tavakkoli, M., Firuzi, O., Saso, L., Suzen, S. Behaviour of 9-Ethyl-9H-carbazole hydrazone derivatives against oxidant systems: Protective effect on amyloid β-induced damage. Croat. Chem. Acta92:87-94 (2019).
65.Gaspar, A., Mohabbati, M., Cagide, F., Razzaghi-Asl, N., Miri, R., Firuzi, O.*, Borges, F. (*Corresponding author) Searching for new cytotoxic agents based on chromen-4-one and chromane-2,4-dione scaffolds.Res. Pharm. Sci.14(1):74-83 (2019).
66.Nejati, M., Sadeghpour, H., Ranjbar, S., Javidnia, K., Edraki, N., Saso, L. Firuzi, O.*, Miri, R. (*Corresponding author) Unsymmetric dihydropyridines bearing 2-pyridyl methyl carboxylate as modulators of P-glycoprotein; Synthesis and biological evaluation in resistant and non-resistant cancer cells. Can. J. Chem.97(8):603-614 (2019).
67.Ranjbar, S., Khonkarn, R., Moreno, A., Baubichon-Cortay, H., Miri, R., Khoshneviszadeh, M., Saso, L., Edraki, N., Falson, P., Firuzi, O.* (*Corresponding author) 5-Oxo-hexahydroquinoline derivatives as modulators of P-gp, MRP1 and BCRP transporters to overcome multidrug resistance in cancer cells. Toxicol. Appl. Pharmacol.362:136-149 (2019).
68.Rahmani-Nezhad, S., Dianat, S., Mahdizadeh, V., Fooladi, Z., Hariri, R., Najafi, Z., Firuzi, O., Vahedi-Mazdabadi, Yg, Farjadmand, F., Akbarzadeh, T., Saeedi, M. Ardekani, M.S. Investigation of polysaccharide extracts from Iranian and French strains of Agaricus subrufescens against enzymes involved in Alzheimer’s disease. Latin Am Carib Bull Med Arom Plant18(6):544-554 (2019).
69.Hosseini, R., Moosavi, F., Silva, T., Rajaian, H., Hosseini, S.Y., Bina, S., Saso, L., Miri, R., Borges, F., Firuzi, O.* (*Corresponding author) Modulation of ERK1/2 and Akt Pathways Involved in the Neurotrophic Action of Caffeic Acid Alkyl Esters. Molecules23:3340 (2018).
70.Kayani, Z., Bordbar, A.-K., Firuzi, O.* (*Corresponding author) Novel folic acid-conjugated doxorubicin loaded β-lactoglobulin nanoparticles induce apoptosis in breast cancer cells. Biomed. Pharmacother.107:945-956 (2018).
71.Ahmadi, R., Hemmateenejad, B., Safavi, A., Shojaeifard, Z., Mohabbati, M., Firuzi, O. Assessment of cytotoxicity of choline chloride-based natural deep eutectic solvents against human HEK-293 cells: A QSAR analysis.Chemosphere209:831-838 (2018).
72.Ebrahimi, M., Firuzi, O., Miri, R., Razzaghi-Asl, N., Ebadi, A. Structural Insight into Binding Mode of 9-Hydroxy Aristolochic Acid, Diclofenac and Indomethacin to PLA2. Interdiscip. Sci.Comput. Life Sci. 10:400-410 (2018).
73.Iraji, A., Firuzi, O., Khoshneviszadeh, M., Nadri, H., Edraki, N., Miri, R. Synthesis and structure-activity relationship study of multi-target triazine derivatives as innovative candidates for treatment of Alzheimer's disease. Bioorg. Chem.77:223-235 (2018).
74.Kayani, Z., Firuzi, O.*, Bordbar, A.K. (*Corresponding author) Doughnut-shaped bovine serum albumin nanoparticles loaded with doxorubicin for overcoming multidrug-resistant in cancer cells. Int. J. Biol. Macromol.107:1835-1843 (2018).
75.Shahraki, O., Zargari, F., Edraki, N., Khoshneviszadeh, M., Firuzi, O., Miri, R. Molecular dynamics simulation and molecular docking studies of 1,4-Dihydropyridines as P-glycoprotein’s allosteric inhibitors. J. Biomol. Struct. Dyn. 36(1):112-125 (2018).
76.Jassbi, A.R., Mirzaie, Y., Firuzi, O., Asadollahi, M. Composition and cytotoxic activity of the essential oils of Mentha mozaffarianii Jamzad at different phenological stages. Curr. Bioact. Comp.14(2):191-196 (2018).
77.Ranjbar, S., Akbari, A., Edraki, N., Khoshneviszadeh, M., Hemmatian, H., Firuzi, O., Khoshneviszadeh, M. 6-Methoxy-3,4-dihydronaphthalenone chalcone-like derivatives as potent tyrosinase inhibitors and radical scavengers. Lett. Drug Des. Discov.15:1170-1179 (2018).
78.Iraji, A., Firuzi, O., Khoshneviszadeh, M., Tavakkoli, M., Mahdavi, M., Nadri, H., Edraki, N., Miri, R. Multifunctional iminochromene-2H-carboxamide derivatives containing different aminomethylene triazole with BACE1 inhibitory, neuroprotective and metal chelating properties targeting Alzheimer's disease. Eur. J. Med. Chem.141:690-702 (2017).
79.Haghighijoo, Z., Firuzi, O., Hemmateenejad, B., Emami, S., Edraki, N., Miri, R. Synthesis and biological evaluation of quinazolinone-based hydrazones with potential use in Alzheimer's disease. Bioorg. Chem.74:126-133 (2017).
80.Menezes, J.C.J.S., Edraki, N, Kamat, SP, Khoshneviszadeh, M, Kayani, Z, Mirzaei, H.H., Miri, R., Erfani, N, Nejati, M., Cavaleiro, J.A.S., Silva, T., Saso, L., Borges, F., Firuzi, O.* (*Corresponding author) Long Chain Alkyl Esters of Hydroxycinnamic Acids as Promising Anticancer Agents: Selective Induction of Apoptosis in Cancer Cells. J. Agric. Food Chem.65(33):7228-7239 (2017).
81.Ebadi, A., Khoshneviszadeh, M., Javidnia, K., Ghahremani, M.H., Firuzi, O.*, Miri, R. (*Corresponding author) 3,4-Dihydropyrimidin-2(1H)-one C5 amides as inhibitors of TNFα production: Synthesis, biological evaluation and molecular modeling. Lett. Drug Des. Discov.14(8): 885-897 (2017).
82.Giovannetti, E., van der Borden, C.L., Frampton, A.E., Ali, A., Firuzi, O., Peters, G.J. Never let it go: Stopping key mechanisms underlying metastasis to fight pancreatic cancer. Semin. Cancer Biol.44:43-59 (2017).
83.Shahraki, O., Edraki, N., Khoshneviszadeh, M., Zargari, F., Ranjbar, S., Saso, L., Firuzi, O.*, Miri, R. (*Corresponding author) Novel 5-oxo-hexahydroquinoline derivatives: design, synthesis, in vitro p-glycoprotein mediated multidrug resistance (MDR) reversal profile and molecular dynamics simulation study. Drug Des. Devel. Ther.11:407-418 (2017).
84.Karimi, Z., Abbasi, S., Shokrollahi, H., Yousefi, G., Fahham, M., Karimi, L., Firuzi, O. Pegylated and amphiphilic Chitosan coated manganese ferrite nanoparticles for pH-sensitive delivery of methotrexate: Synthesis and characterization. Mater. Sci. Eng. C71(1):504-511 (2017).
85.Mirzaei, H.H., Firuzi, O., Baldwin, I.T., Jassbi, A.R. Cytotoxic activities of different Iranian Solanaceae and Lamiaceae plants and bioassay-guided study of an active extract from Salvia lachnocalyx. Nat. Prod. Comm.12(10):1563-1566 (2017).
86.Mirzaei, H.H., Firuzi, O., Schneider, B., Baldwin, I.T., Jassbi, A.R. Cytotoxic diterpenoids from the roots of salvia lachnocalyx. Braz. J. Pharmacogn.27(4): 475-479 (2017).
87.Azimi, S., Zonouzi, A., Firuzi, O., Iraji, A., Saeedi, M., Mahdavi, M., Edraki, N. Discovery of imidazopyridines containing isoindoline-1,3-dione framework as a new class of BACE1 inhibitors: Design, synthesis and SAR analysis. Eur. J. Med. Chem.138:729-737 (2017).
88.Ranjbar, S., Firuzi, O., Edraki, N., Shahraki, O., Saso, L., Khoshneviszadeh, M. Miri, R. Tetrahydroquinolinone derivatives as potent P-glycoprotein inhibitors: Design, synthesis, biological evaluation and molecular docking analysis. MedChemComm.8(10):1919-1933 (2017).
89.Mohammadhosseini, N., Saeedi, M., Moradi, S., Mahdavi, M., Firuzi, O., Foroumadi, A., Shafiee, A. Synthesis and cytotoxicity of novel thioxo-quinazolino[3,4-a]quinazolinones Turk. J. Chem.41:125-134 (2017).
90.Moosavi, F., Hosseini, R., Rajaian, H., Silva, T., Magalhães E Silva, D., Saso, L., Edraki, N., Miri, R., Borges, F., Firuzi, O.* (*Corresponding author) Derivatives of caffeic acid, a natural antioxidant, as the basis for the discovery of novel nonpeptidic neurotrophic agents. Bioorg. Med. Chem.25(12): 3235-3246 (2017).
91.Rezaei, Z., Moghimi, S., Javaheri, R., Asadi, M., Mahdavi, M., Shabani, S., Edraki, N., Firuzi, O., Safavi, M., Amini, M., et al. Synthesis and Biological Evaluation of 1,3,4-Thiadiazole Linked Phthalimide Derivatives as Anticancer Agents. Lett. Drug Des. Discov.14(10):1138-1144 (2017).
92.Carvalho, A.N., Firuzi, O., Gama, M.J., van Horssen, J., Saso, L. Oxidative stress and antioxidants in neurological diseases: is there still hope? Curr. Drug Targets 18(6):705-718 (2017).
93.Edraki, N., Iraji, A., Firuzi, O., Fattahi, Y., Mahdavi, M., Foroumadi, A., Khoshneviszadeh, M., Shafiee, A., Miri, R. 2-Imino 2H-chromene and 2-(phenylimino) 2H-chromene 3-aryl carboxamide derivatives as novel cytotoxic agents: synthesis, biological assay, and molecular docking study. J. Iran. Chem. Soc.13(12):2163-2171 (2016).
94.Hosseini, R., Moosavi, F., Rajaian, H., Silva, T., Magalhães E Silva, D., Soares, P., Saso, L., Edraki, N., Miri, R., Borges, F., Firuzi, O.* (*Corresponding author) Discovery of neurotrophic agents based on hydroxycinnamic acid scaffold. Chem. Biol. Drug Des.88(6):926-937 (2016).
95.Jassbi, A.R., Mirzaei, Y., Firuzi, O., Chandran, J.N., Schneider, B. Bioassay guided purification of cytotoxic natural products from a red alga Dichotomaria obtusata. Braz. J. Pharmacog.26(6):705-709 (2016).
96.Khoshneviszadeh, M., Shahraki, O., Khoshneviszadeh, M., Foroumadi, A., Firuzi, O., Edraki, N., Nadri, H., Moradi, A., Shafiee, A., Miri, R. Structure-based design, synthesis, molecular docking study and biological evaluation of 1,2,4-triazine derivatives acting as COX/15-LOX inhibitors with anti-oxidant activities. J. Enzyme Inhib. Med. Chem.31(6):1602-1611 (2016).
97.Jassbi, A.R., Firuzi, O., Miri, R., Salhei, S., Zare, S., Zare, M., Masroorbabanari, M., Chandran, J.N, Schneider, B., Baldwin, I.T. Cytotoxic activity and chemical constituents of Anthemis mirheydari. Pharm. Biol.54(10): 2044-2049 (2016).
98.Jassbi, A.R., Zare, S., Firuzi, O., Xiao, J. Bioactive phytochemicals from shoots and roots of Salvia species. Phytochem. Rev. 15(5):829-867 (2016).
99.Firuzi, O., Khajehrezaei, S., Ezzatzadegan, S., Nejati, M., Jahanshahi, K., Roozbeh, J. Effects of silymarin on biochemical and oxidative stress markers in end-stage renal disease patients undergoing peritoneal dialysis. Hemodial. Int.20:558–563 (2016).
100.Malhotra, S., Tavakkoli, M., Edraki, N., Miri, R., Sharma, S.K., Prasad, A.K., Saso, L., Len, C., Parmar, V.S., Firuzi, O.* (*Corresponding author) Neuroprotective and Antioxidant Activities of 4-Methylcoumarins: Development of Structure-Activity Relationships. Biol. Pharm. Bull.39(9):1544-1548 (2016).
101.Razzaghi-Asl, N., Miri, R., Firuzi, O.* (*Corresponding author) Assessment of the cytotoxic effect of a series of 1,4-dihydropyridine derivatives against human cancer cells. Iran. J. Pharm. Res.15(3):413-420 (2016).
102.Gurer-Orhan, H., Karaaslan, C., Ozcan, S., Firuzi, O., Tavakkoli, M., Saso, L., Suzen, S. Novel indole-based melatonin analogues: Evaluation of antioxidant activity and protective effect against amyloid β-induced damage. Bioorg. Med. Chem.24(8):1658-1564 (2016).
103.Abbasi, S., Yousefi, G., Firuzi, O., Mohammadi-Samani, S. Design and cell cytotoxicity assessment of palmitoylated polyethylene glycol-grafted chitosan as nanomicelle carrier for paclitaxel. J. Appl. Polymer Sci.133(13):43233 (2016).
104.Almasirad, A., Firoozpour, L., Nejati, M., Edraki, N., Firuzi, O., Khoshneviszadeh, M., Mahdavi, M., Moghimi, S., Safavi, M., Shafiee, A., Foroumadi, A. Design, synthesis, and biological evaluation of new series of 2-amido-1,3,4-thiadiazole derivatives as cytotoxic agents. Z. Naturforsch. B71(3):205-210 (2016).
105.Zarrin, A., Sadighian, S., Rostamizadeh, K., Firuzi, O., Hamidi, M., Mohammadi-Samani, S., Miri, R. Design, preparation, and in vitro characterization of a trimodally-targeted nanomagnetic onco-theranostic system for cancer diagnosis and therapy. Int. J. Pharm.500(1-2):62-76 (2016).
106.Miri, R., Nejati, M., Saso, L., Khakdan, F., Parshad, B., Mathur, D., Parmar, V.S., Bracke, M.E., Prasad, A.K., Sharma, S.K., Firuzi, O.* (*Corresponding author) Structure-activity relationship studies of 4-methylcoumarin derivatives as anticancer agents. Pharm. Biol.54(1):105-110 (2016).
107.Shekari, F., Sadeghpour, H., Javidnia, K., Saso, L., Nazari, F., Firuzi, O.*, Miri, R. (*Corresponding author) Cytotoxic and multidrug resistance reversal activities of novel 1,4-dihydropyridines against human cancer cells. Eur. J. Pharmacol.746(5):233-214 (2015).
108.Moosavi F., Hosseini R., Saso L., Firuzi O.* (*Corresponding author) Modulation of neurotrophic signaling pathways by polyphenols. Drug Des. Devel. Ther.21(10):23-42 (2015).
109.Silva, T, Borges, F., Edraki, N., Alizadeh, M., Miri, R., Saso, L., Firuzi, O.* (*Corresponding author) Hydroxycinnamic acid as a novel scaffold for the development of cyclooxygenase-2 inhibitors. RSC Advances5(72):58902-58911 (2015).
110.Razzaghi-Asl, N., Aggarwal, N, Srivastava, S., Parmar, V.S., Prasad, A.K., Miri, R., Saso, L., Firuzi, O.* (*Corresponding author) Inhibition of Alzheimer’s BACE-1 by 2,6-dialkyl-4-chromon-3-yl-1,4-dihydropyridine-3,5-dicarboxylates. Med. Chem. Res.24(8):3230-3241(2015).
111.Akbarzadeh, T., Noushini, S., Taban, S., Mahdavi, M., Khoshneviszadeh, M., Saeedi, M., Emami, S., …, Firouzi, O., Miri, R., Shafiee, A., Foroumadi, A. Synthesis and cytotoxic activity of novel poly-substituted imidazo[2,1-c][1,2,4]triazin-6-amines. Mol. Divers.19(2):273-281(2015).
112.Esmati, N., Foroughian, M, Saeedi, M., Mahdavi, M., Khoshneviszadeh, M., Firuzi, O., Tanideh, N., Miri, R., Edraki, N., Shafiee, A., Foroumadi, A. Synthesis and cytotoxic activity of some novel dihyrobenzo[h]pyrano [3,2-c]chromene derivatives. J. Heterocyclic Chem.52(1):97-104 (2015).
113.Edraki, N., Firuzi, O., Fatahi, Y., Mahdavi, M., Asadi, M., Emami, S., Divsalar, K., Miri, R, Iraji, A., Khoshneviszadeh, M., Firoozpour, L., Shafiee, A., Foroumadi, A. N-(2-(Piperazin-1-yl)phenyl)arylamide derivatives as β-secretase (BACE1) inhibitors: simple synthesis by Ugi four-component reaction and biological evaluation. Arch. Pharm.(Weinheim). 348(5):330-7 (2015).
114.Miri, R., Firuzi, O., Razzaghi-Asl, N., Javidnia, K., Edraki, N. Inhibitors of Alzheimer's BACE-1 with 3, 5-bis-N-(aryl/heteroaryl) carbamoyl-4-aryl-1,4-dihydropyridine structure. Arch. Pharm. Res.38(4):456-69 (2015).
115.Saso, L., Firuzi, O*. (*Corresponding author) Pharmacological applications of antioxidants: lights and shadows. Curr. Drug Targets.15(13):1177-99 (2014).
116.Nikkhoo, A. R., Miri, R., Arianpour, N., Firuzi, O., Ebadi, A., Salarian, A. A. Cytotoxic activity assessment and c-Src tyrosine kinase docking simulation of thieno[2, 3-b] pyridine-based derivatives. Med. Chem. Res.23 (3):1225-33 (2014).
117.Mohammadi, M. K., Firuzi, O., Khoshneviszadeh, M., Razzaghi-Asl, N., Sepehri, S., Miri, R. Novel 9-(alkylthio)-acenaphtho[1, 2-e]-1, 2, 4-triazine derivatives: Synthesis, cytotoxic activity and molecular docking studies on B-cell lymphoma 2 (Bcl-2). Daru. 6;22(1):2(2014).
118.Navidpour, L., Amini, M., Miri, R., Firuzi, O., Tavakkoli, M., Shafiee, A. Synthetic approaches towards the sulfonamide substituted-1, 5-diarylimidazole-2-thiones as selective cyclooxygense-2 inhibitors. J. Heterocyclic Chem.51(1):71-79 (2014).
119.Motamedi, R., Shafiee, A., Rezai, M. R., Firuzi, O., Edraki, N., Miri, R. Oxidative aromatization, cytotoxic activity evaluation and conformational study of novel 7-aryl-10, 11-dihydro-7h-chromeno [4, 3-b]quinoline-6, 8(9h, 12h)-dione derivatives. Iran J. Pharm. Res.13(1):103-14(2014).
120.Jassbi, A. R., Miri, R., Asadollahi, M., Javanmardi, N., Firuzi, O.* (*Corresponding author) Cytotoxic, antioxidant and antimicrobial effects of nine species of woundwort (Stachys) plants. Pharm. Biol.52(1):62-7 (2014).
124.Razzaghi-Asl, N., Garrido, J., Khazraei, H., Borges, F., Firuzi, O.* Antioxidant properties of hydroxycinnamic acids: a review of structure-activity relationships. Curr. Med. Chem.20(36):4436-50 (2013). (*Corresponding author)
125.Firuzi, O., Miri, R., Asadollahi, M., Eslami, S., Jassbi, A. R. Cytotoxic, Antioxidant and Antimicrobial activities and phenolic contents of eleven Salvia species from Iran.Iran. J. Pharm. Res.12(4):801-810 (2013).
126.Razzaghi-Asl, N., Firuzi, O., Hemmateenejad, B., Javidnia, K., Edraki, N., Miri, R. Design and synthesis of novel 3, 5-bis-N-(aryl/heteroaryl) carbamoyl-4-aryl-1, 4-dihydropyridines as small molecule BACE-1 inhibitors. Bioorg. Med. Chem.21(22):6893-909 (2013).
127.Firuzi, O., Javidnia, K., Mansourabadi, E., Saso, L., Mehdipour, A. R., Miri, R. Reversal of multidrug resistance in cancer cells by novel asymmetrical 1, 4-dihydropyridines. Arch. Pharm. Res.36(11):1392-402 (2013).
128.Khoshneviszadeh, M., Ghahremani, M. H., Foroumadi, A., Miri, R., Firuzi, O., Madadkar-Sobhani, A., Edraki, N., Parsa, M., Shafiee, A. Design, synthesis and biological evaluation of novel anti-cytokine 1, 2, 4-triazine derivatives. Bioorg. Med. Chem.21(21):6708-6717 (2013).
129.Molaverdi, F., Khoobi, M., Emami, S., Alipour, M., Firuzi, O., Foroumadi, A., Dehghan, G., Miri, R., Shaki, F., Jafarpour, F., Shafiee, A. Polyoxygenated cinnamoylcoumarins as conformationally constrained analogs of cytotoxic diarylpentanoids: Synthesis and biological activity. Eur. J. Med. Chem.8(68):103-110 (2013).
130.Shahrisa, A., Esmati, S., Miri, R., Firuzi, O., Edraki, N., Nejati, M. Cytotoxic activity assessment, QSAR and docking study of novel bis-carboxamide derivatives of 4-pyrones synthesized by Ugi four-component reaction. Eur. J. Med. Chem.66:388-99 (2013).
131.Shahabipour, S., Firuzi, O., Asadollahi, M., Faghihmirzaei, E., Javidnia, K. Essential oil composition and cytotoxic activity of Ducrosia anethifolia and Ducrosia flabellifolia from Iran. J. Ess. Oil Res.25(2):160-63 (2013).
132.Edraki, N., Firuzi, O., Foroumadi, A., Miri, R., Madadkar-Sobhani, A., Khoshneviszadeh, M., Shafiee, A. Phenylimino-2H-chromen-3-carboxamide derivatives as novel small molecule inhibitors of β-Secretase (BACE1). Biororg. Med. Chem. 21(8):2396-2412 (2013).
133.Sarkarzadeh, H., Miri, R., Firuzi, O., Amini, M., Razzaghi-Asl, N., Edraki, N., Shafiee, A. Synthesis and antiproliferative activity evaluation of imidazole-based indeno[1, 2-b]quinoline-9, 11-dione derivatives. Arch. Pharm. Res.36(4):436-47 (2013).
134.Firuzi, O., Shakibazad, N., Amoozgar, H., Borzoee, M., Abtahi, S., Ajami, G., Ardi, P., Miri, R. Effects of omega-3 polyunsaturated fatty acids on heart function and oxidative stress biomarkers in pediatric patients with dilated cardiomyopathy. Int. Cardiovasc. Res. J.7(1):8-14 (2013).
135.Azizmohammadi M., Khoobi M., Ramazani A., Emami S., Zarrin A., Firuzi O., Miri R., Shafiee A. 2H-chromene derivatives bearing thiazolidine-2, 4-dione, rhodanine or hydantoin moieties as potential anticancer agents. Eur. J. Med. Chem. 2(59C):15-22 (2013).
136.Azizian, J., Mohammadi, M. K., Firuzi, O., Razzaghi-asl, N., Miri, R.Med.Chem. Res.21(11):3730-3740 (2012). Synthesis, biological activity and docking study of some new isatin Schiff base derivatives.
137.Ghalib, R.M., Hashim, R., Mehdi, S. H., Sulaiman, O., Pereira Silva, P. S., Jassbi, A. R., Firuzi, O., Kawamura, F., Chan, K. -L., Murugaiyah, V. Synthesis of ninhydrin derivatives and their anticancer, antimicrobial and cholinesterase enzymes inhibitory activities. Lett. Drug Des. Discov.9(8):767-74 (2012).
138.Hemmateenejad, B., Shamsipur, M., Khosousi, T., Shanehsaz, M., Firuzi, O. Antioxidant activity assay based on the inhibition of oxidation and photobleaching of l-cysteine-capped CdTe quantum dots. Analyst. 137(17):4029-36 (2012).
139.Garrido, J., Gaspar, A., Garrido, EM., Miri, R., Tavakkoli, M., Pourali, S., Saso, L., Borges, F., Firuzi, O.* (*Corresponding author) Alkyl esters of hydroxycinnamic acids with improved antioxidant activity and lipophilicity protect PC12 cells against oxidative stress. Biochimie.94(4):961-7 (2012).
140.Miri, R., Saadati, H., Ardi, P., Firuzi, O.* (*Corresponding author) Alterations in oxidative stress biomarkers associated with mild hyperlipidemia and smoking. Food Chem.Toxicol.50(3-4):920-6 (2012).
141.Kancheva, V. D., Saso, L, Angelova, SE, Foti, M. C., Slavova-Kasakova, A., Daquino, C., Enchev, V., Firuzi, O., Nechev, J.Biochimie.94(2):403-15 (2012). Antiradical and antioxidant activities of new bio-antioxidants.
143.Jamalian, A., Miri, R., Firuzi, O., Amini, M., Moosavi-Movahedi, A. A., Shafiee, A. Synthesis, cytotoxicity and calcium antagonist activity of novel imidazolyl derivatives of 1, 8-acridinediones. J. Iran. Chem. Soc.8(4):983-991 (2011).
144.Firuzi, O.*, Miri, R., Tavakkoli, M., Saso, L. (*Corresponding author) Antioxidant Therapy: Current Status and Future Prospects. Curr. Med. Chem.18(25):3871-88 (2011).
145.Miri, R., Firuzi, O., Peymani, P., Nazarian, Z., Shafiee, A. Synthesis and Cytotoxicity Study of New Cyclopenta [b] quinoline-1, 8-dione Derivatives. Iran. J. Pharmaceut. Res.10(3):489-96 (2011).
146.Shafiee, A., Motamedi, R., Firuzi, O., Meili, S, Mehdipour, A. R., Miri, R.Med.Chem. Res.20:466-74 (2011). Synthesis and cytotoxic activity of novel benzopyrano[3, 2-c]chromene-6, 8-dione derivatives.
147.Alizadeh, A., Khosh-khui, M., Javidnia, K., Firuzi, O., Jokar, S. M. Chemical composition of the essential oil, total phenolic content and antioxidant activity in Origanummajoranal. (Lamiaceae) cultivated in Iran. Adv. Environ. Biol.5(8):2326-31 (2011).
148.Miri, R., Motamedi, R., Rezaei, M. R., Firuzi, O., Javidnia, A., Shafiee, A.Design, Synthesis and evaluation of cytotoxicity of novel chromeno[4, 3-b]quinoline derivatives. Arch. Pharm. (Weinheim)344(2):111-8 (2010).
149.Gaspar, A., Martins, M., Silva, P., Garrido, E. M., Garrido, J., Firuzi, O.*, Miri, R., Saso, L., Borges, F. (*Corresponding author) Dietary phenolic acids and derivatives:Evaluation of the antioxidant activity of sinapic acid and its alkyl esters. J. Agric. Food Chem. 58(21):11273-80 (2010).
150.Moradi, A., Navidpour, L., Amini, M., Sadeghian, H., Shadnia, H., Firouzi, O., Miri, R., Ebrahimi, S. E., Abdollahi, M., Zahmatkesh, M. H., Shafiee, A. Design and synthesis of 2-phenoxynicotinic acid hydrazides as anti-inflammatory and analgesic agents. Arch. Pharm. (Weinheim)343(9):509-18 (2010).
151.Morabito, G., Trombetta, D., Singh, K., Prasad, K., Parmar, S., Naccari, C., Mancari, F., Saija, A., Cristani, M., Firuzi, O., Saso, L. Antioxidant properties of 4-methylcoumarins in in vitro cell-free systems. Biochimie92(9):1101-7 (2010).
152.Firuzi, O., Asadollahi, M., Gholami, M., Javidnia, K. Composition and biological activities of essential oils from four Heracleum species. Food Chem.122(1):117-22 (2010).
153.Firuzi, O.*, Javidnia, K., Gholami, M., Soltani, M., Miri, R. (*Corresponding author) Antioxidant activity and total phenolic content of 24 Lamiaceae species growing in Iran. Nat. Prod. Commun.5(2):261-4 (2010).
154.Azizian, J., Mohammadi, M. K., Firuzi, O., Mirza, B., Miri, R. Microwave-assisted solvent-free synthesis of bis(dihydropyrimidinone)benzenes and evaluation of their cytotoxic activity. Chem. Biol. Drug Des.75(4):375-80 (2010).
155.Schultz. Bip. Javidnia, K., Gholami, M., Firuzi, O., Özer, H., Kandemir, A. Antimicrobial and antioxidant activity and chemical composition of the essential oil of tanacetummacrophyllum (Waldst. et Kit. ) J. Ess. Oil Res.22(2):186-8 (2010).
156.Alizadeh, A., Khoshkhui, M., Javidnia, K., Firuzi, O., Tafazoli, E., Khalighi, A. Effects of fertilizer on yield, essential oil composition, total phenolic content and antioxidant activity in Satureja hortensis L. (Lamiaceae) cultivated in Iran. J. Med. Plant Res.4(1):033-040 (2010).
157.Firuzi, O., Spadaro, A., Spadaro, C., Riccieri, V., Petrucci, R., Marrosu, G., Saso, L. Protein oxidation markers in the serum and synovial fluid of psoriatic arthritis patients. J. Clin. Lab. Anal. 22(3):210-5 (2008).
158.Firuzi, O., Zhuo, J., Chinnici, C. M., Wisniewski, T., Pratico, D. 5-lipoxygenase gene disruption reduces amyloid-β pathology in a mouse model of Alzheimer’s disease. Faseb J.22(4):1169-78 (2008).
159.Riccieri, V., Spadaro, A., Fuksa, L., Firuzi, O., Saso, L., Valesini, G. Specific oxidative stress parameters differently correlate with nailfold capillaroscopy changes in systemic sclerosis. Clin. Rheumatol.27(2):225-30 (2008).
160.Croce, A., Firuzi, O., Altieri, F., Eufemi, M., Agostino, R., Priori, M, Valesini, G., Saso, L. Effect of infliximab on the glycosylation of IgG in patients with rheumatoid arthritis. J. Clin. Lab. Anal.21:303-14(2007).
161.Schmalhausen, E. V., Zhlobek, E. B., Shalova, I. N., Firuzi, O., Saso, L., Muronetz, V. I. Antioxidant and pro-oxidant effects of quercetin on glyceraldehyde-3-phosphate dehydrogenase. Food Chem. Toxicol.45:1988-93 (2007).
162.Petrucci, R., Marrosu, G., Astolfi, P., Firuzi, O., Saso, L., Greci, L. A Spectroelectrochemical and chemical study on oxidation of hydroxycinnamic acids in aprotic medium. Electrochim. Acta.52:2461-70 (2007).
163.Firuzi, O., Mladenka, P., Riccieri, V., Spadaro, A., Petrucci, R., Marrosu, G., Saso, L. Parameters of oxidative stress status in healthy subjects; their correlations and stability after sample collection. J. Clin. Lab. Anal.20:1-10 (2006).
164.Firuzi, O., Fuksa, L., Spadaro, C., Boušová, I, Riccieri, V., Spadaro, A., Petrucci, R., Marrosu, G., Saso, L. Oxidative stress parameters in different systemic rheumatic diseases.J. Pharm. Pharmacol. 58:951-7 (2006).
165.Firuzi, O., Praticò, D. Coxibs and Alzheimer’s disease: Should they stay or should they go?Ann. Neurol.59:219-28 (2006).
166.Daniele, C., Dahamna, S., Firuzi, O., Sekfali, N., Saso, L., Mazzanti, G. Atractylisgummifera L. poisoning: an ethnopharmacological review.J. Ethnopharmacol.97:175-81 (2005).
167.Firuzi, O., Lacanna, A., Petrucci, R., Marrosu, G., Saso, L. Evaluation of the antioxidant activity of flavonoids by "ferric reducing antioxidant power" assay and cyclic voltammetry.Biochim. Biophys. Acta1721:174-84 (2005).
168.Firuzi, O., Mladenka, P., Petrucci, R., Marrosu, G., Saso, L. Hypochlorite scavenging activity of flavonoids. J. Pharm. Pharmacol.56:801-7 (2004).
169.Firuzi, O., Giansanti, L., Vento, R., Seibert, C., Petrucci, R., Marrosu, G., Agostino, R., Saso, L. Hypochlorite scavenging activity of hydroxycinnamic acids evaluated by a rapid microplate method based on the measurement of chloramines. J. Pharm. Pharmacol. 55:1021-7 (2003).
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