مرکز تحقیقات شیمی دارویی و گیاهی | Publications
محققان دانشجویاننقشه سایت
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  1. Moheimanian N., Mirkhani H., Edraki N., Poustforoosh A., Momeni S., Khalighian N., Zidorn C., Sohrabipour J., Jassbi A. R. Bioassay-guided purification of α-glucosidase inhibitor fatty acids from Padina tetrastromatica. J Appl Phycol. 2023; 1-12
  2. Moheimanian N., Mirkhani H., Purkhosrow A., Sohrabipour J., Jassbi A. R. In vitro and in vivo antidiabetic, α-glucosidase inhibition and antibacterial activities of three brown algae, Polycladia myrica, Padina antillarum, and Sargassum boveanum, and a red alga, Palisada perforata from the Persian gulf. Iran J Pharm Res. 2023; 22: e133731
  3. Nazari S., Mirkhani H. Cardiorenal protections of SGLT2 inhibitors in the treatment of type 2 diabetes. Curr Diabetes Rev. 2023; 19: 46-61.
  4. Doostkam A., Mirkhani H., Iravani K., Karbalay-Doust S., Doosti A., Nadimi E., Pirsalami F. Controversial role of folic acid on diabetic auditory neuropathy. ACS Pharmacol Transl Sci. 2022; 5: 985-992.
  5. Goharinia M., Mirkhani H. RGS4 inhibition and the effects of adrenoceptor and cholinoceptor agonists on isolated left atrium and aorta of normal and diabetic rats. Physiol. Pharmacol. 2022; 26: 178-187.
  6. Moheimanian N., Mirkhani H., Sohrabipour J., Jassbi A. R. inhibitory potential of six brown algae from the persian gulf on α-glucosidase and in vivo antidiabetic effect of Sirophysalis trinodis. Iran J. Med. Sci. 2022; 47: 484-493.
  7. Doostkam A., Fathalipour M., Anbardar M. H., Purkhosrow A., Mirkhani H. Therapeutic effects of milk thistle (Silybum marianum l.) and artichoke (Cynara scolymus l.) on nonalcoholic fatty liver disease in type 2 diabetic rats. Can. J. Gastroenterol. Hepatol. 2022; doi: 10.1155/2022/2868904
  8. Doostkam A., Mirkhani H., Iravani K., Karbalay-Doust S., Zarei K. Effect of rutin on diabetic auditory neuropathy in an experimental rat model. Clin. Exp. Otorhinolaryngol. 2021; 14: 259-267.
  9. Doorandishan M., Gholami M., Mirkhani H., Ebrahimi P., Jassbi A. R. α- Glucosidase inhibitory and antioxidant activities of Moluccella aucheri (boiss.) scheen extracts. J. Fasa. Univ. Med. Sci. 2021; 11: 3839-3847.
  10. Khazraei H., Akmali M., Mirkhani H. Mechanical effects of ranolazine on normal and diabetic-isolated rat heart. Res. Pharm. Sci. 2021; 16: 269-277.
  11. Khazraei H., Mirkhani H., Shabbir W. Electrocardiological effects of ranolazine and lidocaine on normal and diabetic rat atrium. J. Interv. Card. Electrophysiol. 2021; 60: 387-394.
  12. Zare S., Mirkhani H., Firuzi O., Moheimanian N., Asadollahi M., Pirhadi S., Chandran J. N., Schneider B., Jassbi A. R. Antidiabetic and cytotoxic polyhydroxylated oleanane and ursane type triterpinoids from Salvia grossheimii. Bioorg. Chem. 2020; 104: 104297.
  13. Fathalipour M., Fathalipour H., Safa O., Nowrouzi-Sohrabi P., Mirkhani H.,  Hassanipour S. The therapeutic role of carotenoids in diabetic retinopathy: a systematic review.Diabetes. Metab. Syndr. Obes. 2020; 13: 2347-2358.
  14. Fathalipour M., Mahmoodzadeh A., Safa O., Mirkhani H. Puerarin as potential treatment in diabetic retinopathy. J. Herbmed. Pharmacol. 2020; 9: 105-111.
  15. Fathalipour M., Eghtedari M., Borges F., Silva T., Moosavi F., Firuzi O., Mirkhani H. Caffeic Acid Alkyl amide derivatives ameliorate oxidative stress and modulate ERK1/2 and AKT signaling pathways in a rat model of diabetic retinopathy. Chem. Biodivers. 2019; 16: e1900405.
  16. Fathalipour M., Mirkhani H., Goharinia M. Effect of allopurinol and benzbromarone on diabetic cardiomyopathy and vasculopathy in streptozotocin- induced diabetic rats. Physiol. Pharmacol. 2019; 23:1-8.
  17. Behrouz S., Soltani Rad M. N., Taghavi Shahraki B., Fathalipour M., Behrouz M., Mirkhani H. Design, synthesis, and in silico studies of novel eugenyloxy propanol azole derivatives having potent antinociceptive activity and evaluation of their β-adrenoceptor blocking property. Mol. Divers. 2019; 23: 147-164.
  18. Mesbah F., Bordbar H., Talaei Khozani T., Dehghani F., Mirkhani H. The non-preventive effects of human menopausal gonadotropins on ovarian tissues in nandrolone decanoate-treated female rats: A histochemical and ultra-structural study. Int. J. Reprod. Biomed (Yazd). 2018; 16: 159-174.
  19. Talebianpoor M. S., Owji S. M., Goharinia M., Mirkhani H. Effect of tempol, a synthetic antioxidant, on renal complications of L-NAME induced preeclampsia in rat. Physiol. Pharmacol. 2017; 21: 241-250.
  20. Aliabadi E., Namavar M. R., Mortezaee K., Toolee H., Keshtgar S., Mirkhani H., Akbari M., Rastegar T., Solhjoo S. Kisspeptin expression features in the arcuate and anteroventral periventricular nuclei of hypothalamus of letrozole-induced polycystic ovarian syndrome in rats. Arch. Gynecol. Obstet. 2017; 296: 957-963.
  21. Kamali F., Mirkhani H., Nematollahi A., Heidari S., Moosavi E., Mohamadi M. The effect of transcutaneous electrical nerve stimulation of sympathetic ganglionsand acupuncture points on distal blood flow. J. Acupunct. Meridian. Stud. 2017; 10: 120-124.
  22. Goharinia M., Zareei A., Rahimi M., Mirkhani H. Can allopurinol improve retinopathy in diabetic rats? Oxidative stress or uric acid; which one is the culprit? Res. Pharm. Sci. 2017; 12: 401-408.
  23. Shafa M., Haddad M., Rafieossadat R., Mirkhani H. Use of vasodilators to overcome perioperative spasm of the left internal mammary artery and saphenous vein in coronary artery bypass grafting: comparison of papaverine and glyceryl trinitrate/verapamil combination. Int. Cardio. Res. J. 2017; 11: e10564.
  24. Khazraei H., Mirkhani H., Akmali M. The antianginal agent ranolazine inhibits mitochondrial β-oxidation pathway. Clin. Exp. Pharmacol. 2016; DOI: 10.4172/2161-1459.1000203.
  25. Mesbah F., Moslem M., Vojdani Z., Mirkhani H., Does metformin improve in vitro maturation and ultrastructure of oocytes retrieved from estradiol valerate polycystic ovary syndrome-induced rats. J. Ovarian. Res. 2015; 8: DOI 10.1186/s13048-015-0203-x.
  26. Shirazi M., Mirkhani H., Monabbati A., Moghtadernejad S., Aminsharifi A., The effect of pentoxifylline on detrusor muscle contractility after partial urethral obstruction in a rat model. Int. Urol. Nephrol. 2015; 47: 1493-1497.
  27. Sedigh-Ardekani M., Sahmeddini M. A., Sattarahmady N., Mirkhani H., Lactic acidosis treatment by nanomole level of spermidine in an animal model. Regul. Toxicol. Pharmacol. 2015; 70: 514-518.
  28. Khazraei H., Shafa M., Mirkhani H., Effect of ranolazine on cardiac microcirculation in normal and diabetic rats, Acta Physiol. Hung. 2014; 101: 301-308.
  29. Yousefimanesh H., Abdolahi F., Jahromi B. M., Bagheri M., Noorafshan A., Zarifkar A., Mirkhani H. Effect of intradermal injection of heparinase III on skin wound healing in diabetic rats. G. Ital. Dermatol. Venereol. 2014; 149: 427-433.
  30. Bordbar H., Mesbah F., Talaei T., Dehghani F., Mirkhani H., Modulatory effect of gonadotropins on rats' ovaries after nandrolone decanoate administration: A stereological study. Iran. J. Med. Sci. 2014; 39: 44-50.
  31. Noorafshan A.,  Karbalay-Doust S., Khazraei H.,  Rafati A.,  Mirkhani H. Spatial arrangement of the heart structure: Application of second-order stereology in diabetic rats . Ann .Anat. 2014: 196: 20-25.
  32. Khazraei H., Mirkhani H., Purkhosrow A. Vasorelaxant effect of ranolazine on isolated normal and diabetic rat aorta: a study of possible mechanisms. Acta. Physiol. Hung. 2013; 100: 153-162.
  33. Noorafshan A., Khazraei H., Mirkhani H., Karbalay-Doust S. Stereological study of the diabetic heart of male rats. Lab. Anim. Res. 2013; 29: 12-18.
  34. Talebianpoor M. S., Mirkhani H. The effect of tempol administration on the aortic contractile responses in rat preeclampsia model. ISRN Pharmacol. 2012; 187208. Epub 2012 Sep 3.
  35. Aliabadi E., Mehranjani M. S., Borzoei Z., Talaei-Khozani T., Mirkhani H., Tabesh H. Effects of L-carnitine and L-acetyl-carnitine on testicular sperm motility and chromatin quality. Iran. J. Reprod. Med. 2012; 10: 77-82.
  36. Vessal G., Khabiri A., Mirkhani H., Cookson B. D., Askarian M. Study of antibiotic prescribing among dental practitioners in Shiraz, Islamic Republic of Iran. East. Mediterr. Health J. 2011; 17: 763-769.
  37. Bagheri M., Jahromi B. M., Mirkhani H., Solhjou Z., Noorafshan A., Zamani A., Amirghofran Z. Azelnidipine, a new calcium channel blocker, promotes skin wound healing in diabetic rats. J. Surg. Res. 2011; 169: e101-107.
  38. Mesbah F., Bahri A., Ghasemi E., Khozani T. T., Mirkhani H., Parsanezhad M. E. The effects of metformin on ovum implantation and pregnancy outcome in rats with induced PCOS. Tehran Univ. Med. J. 2011; 69: 191-197.
  39. Noorafshan A., Karbalay-Doust S., Valizadeh A., Aliabadi E., Mirkhani H. Ameliorative effects of curcumin on the seminiferous epithelium in metronidazole-treated mice: a stereological study. Toxicol.  Pathol. 2010; 38: 366-371.
  40. Mesbah F., Moslem M., Vojdani Z., Mirkhani H. Estradiol induced polycystic ovary syndrome: an animal study. Armaghan-e Danesh 2010; 15: 325-334.
  41. Davarmanesh M., Mardani M., Mirkhani H., Monabbati A.,Tanideh N., Mehrabani D. Effect of dexamethasone premedication on oral mucositis in hamster. J. Appl. Animal Res. 2009; 36: 267-270.
  42. Mirkhani H., Fadakar P. Knowledge, attitude and practice of physicians in appropriate prescription of organic nitrates in Iran. Iranian J. Pharmacol. Ther. 2009; 8: 83-86.
  43. Mirkhani H., Shafa M., Khazraei H. Comparison of the effects of levosimendan and papaverine on human internal mammary artery and saphenous vein. Cardiovas. Drugs Ther. 2009; 23: 355-359.
  44.  محمدشریف طالبیان‌پور، حسین میرخانی.  اثرات فنیل‌افرین، کلسیم، استیل‌کولین و دیازوکساید بر آئورت مجزای موش‌های صحرایی پری‌اکلامپتیک. ارمغان دانش (1388) شماره 54، صفحه 29-17.
  45.  امین کوهپایه، حسین میرخانی، علی اکبر نکوئیان، دیوید سنت.  تعیین تأثیر هسپریدین بر اختلال عملکردی قلب ناشی از دیابت نوع 1 در موش‌های صحرایی. ارمغان دانش (1388) شماره 53، صفحه 35-25.
  46. صدیقه شایق، حسین میرخانی، لیلا بذر افکن. دیدگاه دانشجویان دانشگاه علوم پزشکی شیراز در مورد تاثیر برنامه روز معرفی دانشگاه بر انتخاب رشته تحصیلی. گام های توسعه در آموزش پزشکی (1388)، مجلد 6، صفحه 49-40.
     
  47. Samzadeh-Kermani A., Shafaroodi H., Miri R., Mirkhani H., Vosooghi M., Shafiee A. Lipophilic 2-(4-chlorophenyl)-4-thiazolyl-1,4-dihydropyridines: synthesis, calcium channel antagonist activity, and protection against pentylenetetrazole-induced seizure. Medicinal Chem. Res. 2009; 18: 112-126.
  48. Miri R., Javidnia K., Mirkhani H., Kazemi F., Hemmateenejad B, Edraki N., Mehdipour, A.R. Synthesis and in vitro dual calcium channel antagonist-agonist activity of some 1, 4-Dihydo-2,6-dimethyl-3-nitro and cyano-4-(1-methyl-5-nitro-1H-imidazol- 2-yl)-5-pyridinecarboxylates. Daru 2008; 16: 263-270.
  49. Mesbah S. F., Shokri S., Karbalay-Doust S., Mirkhani H. Effects of nandrolone decanoate on ultrastructure of testis in male adult rats. Iran. J. Med. Sci. 2008; 33: 94-100.
  50. Kouhpayeh A., Mirkhani H., Nekooeian AA. Improvement of endothelium-dependent relaxation of rat models type 1 and type 2 by hesperidine. Iran. Cardiovasc. Res. J. 2008; 1: 200-207.
  51. Hosseini M., Miri R., Amini M., Mirkhani H., Hemmateenejad B., Ghodsi S., Alipour E., Shafiee A. Synthesis, QSAR and calcium channel antagonist activity of new 1,4-dihydropyridine derivatives containing 1-methy 1-4,5-dichloroimidazolyl substituents. Archiv. Pharmazie. 2007; 340: 549-556.
  52. Mesbah S. F., Shokri S., Karbalay-doust S., Mirkhani H. The effect of nandrolone decanoate on the body, testis and epididymis weight and semen parameters in adult male rat. Iran. J. Med. Sci. 2007; 32: 93-99.
  53. Miri R., Javidnia K., Mirkhani H., Hemmateenejad B., Sepeher Z., Zalpour M., Behzad T., Khoshneviszadeh M., Edraki N., Mehdipour A. R. Synthesis, QSAR and calcium channel modulator activity of new hexahydroquinoline derivatives containing nitroimidazole. Chem. Biol. Drug Des. 2007; 70: 329-336.
  54. Karbalay-Doust S., Noorafshan A., Ardekani F. M., Mirkhani H. The reversibility of sperm quality after discontinuing nandrolone decanoate in adult male rats. Asian J. Androl. 2007; 9: 235-239.
  55. Daryabari N., Akbarzadeh T., Amini M, Miri R., Mirkhani H., Shafiee A. Synthesis and calcium channel antagonist activities of new derivatives of dialkyl 1,4-dihydro-2,6-dimethyl-4-(5-phenylisoxazol-3-yl)pyridine-3,5- dicarboxylates. J. Iranian Chemical Society. 2007; 4: 30-36.
  56. Ghodsi S., Alipour E., Amini M.,  Miri R., Tagi-ganji K. M., Hosseini M., Mirkhani H., Shafiee A.  The synthesis and characterization of new asymmetrical dihydropyridine derivatives containing a 2,4-dichloro-5-thiazolyl substituent. Phosphorus, Sulfur, and Silicon. 2006; 181: 2435-2444.
  57. Askarian M., Moravejji A.R., Mirkhani H., Namazi S., Weed H. Adherence to American Society of Health-system Pharmacists (ASHP) surgical antibiotic prophylaxis guidelines in Shiraz, , Iran. Infect. Control Hosp. Epidemiol. 2006; 27: 876-878.
  58. Mirkhani H., Golbahar J., Shokri S. Chronic administration of nandrolone decanoate does not increase the plasma homocysteine level of male rats. Basic Clin. Pharmacol. Toxicol. 2005; 97: 214-217.
  59. Mirkhani H., Dirin M., Youssef-Zayeh I. Mechanism of vasoselective action of mebudipine, a new calcium channel blocker. Vasc. Pharmacol. 2005; 42: 23-29.
  60. Mirkhani H., Omrani G. R., Ghiaee S., Mahmoudian M.  Effects of mebudipine and dibudipine, two new calcium channel blockers, on rat left atrium, rat blood pressure and human internal mammary artery. J. Pharm. Pharmacol. 1999; 51: 617-622.
  61. Mahmoudian M., Shafiei M., Mirkhani H., Omrani G. R. Effects of different vasodilators on human internal mammary artery in vitro. Adv. Exp. Med. Biol.1999; 471: 419-426.
  62. Mahmoudian M., Mirkhani H. Effect of diazoxide, an ATP-dependent potassium-channel opener, on isolated aortae of normal and diabetic rats. Gen. Pharmacol. 1998; 31: 569-571.
  63. Mahmoudian  M., Mirkhani H., Nehardani Z., Ghiaee s. Synthesis and biological activity of two new calcium-channel blockers, mebudipine and dibudipine. J. Pharm. Pharmacol. 1997; 49: 1229-1233.